Some people benefit from alcoholism

Alcohol Addiction: New Drugs for Alcoholics

Literature tip

Ants, O .: The end of my addiction. Kunstmann, Munich 2013
The French doctor Olivier Ameisen describes how he combated his alcohol addiction with baclofen.


Ameisen, O .: Complete and Prolonged Suppression of Symptoms and Consequences of Alcohol-Dependence Using High-Dose Baclofen: A Self-Case Report of a Physician. In: Alcohol and Alcoholism 40, pp. 147-150, 2005

Beraha, E. M. et al .: Efficacy and Safety of High-Dose Baclofen for the Treatment of Alcohol Dependence: A Multicentre, Randomized, Double-Blind Controlled Trial. In: European Neuropsychopharmacology 26, pp. 1950-1959, 2016

van den Brink, W. et al .: Efficacy of As-Needed Nalmefene in Alcohol-Dependent Patients with at Least a High Drinking Risk Level: Results from a Subgroup Analysis of Two Randomized Controlled 6-Month Studies. In: Alcohol and Alcoholism 48, pp. 570-578, 2013

Gual, A. et al .: A Randomized, Double-Blind, Placebo-Controlled, Efficacy Study of Nalmefene, As-Needed Use, in Patients with Alcohol Dependence. In: European Neuropsychopharmacology 23, pp. 1432-1442, 2013

Heilig, M. et al .: The Need for Treatment Responsive Translational Biomarkers in Alcoholism Research. In: Robbins, T. W., Sahakian, B. J. (Ed.): Current Topics in Behavioral Neurosciences 28: Translational Neuropsychopharmacology. Springer, Heidelberg 2016, pp. 151-171

Jaury, P .: High Dose Baclofen for the Treatment of Alcohol Drinkers (BACLOVILLE). ISBRA ESBRA World Congress on Alcohol and Alcoholism, Berlin, 2-5 September 2016

Jonas, D. E. et al .: Pharmacotherapy for Adults with Alcohol Use Disorders in Outpatient Settings. A Systematic Review and Meta-Analysis. In: Journal of the American Medical Association 311, pp. 1889-1900, 2014

Mann, K. et al .: Extending the Treatment Options in Alcohol Dependence: A Randomized Controlled Study of As-Needed Nalmefene. In: Biological Psychiatry 73, pp. 706-713, 2013

Müller, C. A. et al .: High-Dose Baclofen for the Treatment of Alcohol Dependence (BACLAD Study): A Randomized, Placebo-Controlled Trial. In: European Neuropsychopharmacology 25, pp. 1167-1177, 2015

Reynaud, M. et al .: A Randomized, Double Blind, Placebo-Controlled Efficacy Study of High-Dose Baclofen in Alcohol Dependent Patients: The ALPADIR Study. ISBRA ESBRA World Congress on Alcohol and Alcoholism, Berlin, 2-5 September 2016

Schacht, J. R. et al .: Predictors of Naltrexone Response in a Randomized Trial: Reward-Related Brain Activation, OPRM1 Genotype, and Smoking Status. In: Neuropsychopharmacology 10.1038 / npp.2017.74, 2017